ubiquitin enzyme probes online manufacturer Manufacturer

Ub-ACC,Catalog Number: U1020,Lyophilized,Purity95%,Molecular Weight:8765.4 Ubiquitin-ACC is prepared by the C-terminal derivatization of ubiquitin with 7-amino-4-carbamoylmethylcoumarin. Ubiquitin-ACC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin specific proteases (USPs). It is a particularly useful reagent for the study of deubiquitinating activity where detection sensitivity

Ub-AMC,Catalog Number: U1010,Lyophilized,Purity95% Ubiquitin-AMC is prepared by the C-terminal derivatization of ubiquitin with 7-amino-4-methylcoumarin. Substrate for deubiquitinylating enzyme activity assays. Identification/confirmation of enzyme deubiquitinylation activity. Investigation of deconjugating enzyme substrate specificity in comparison with alternative UBL substrates. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe

Dha-K63-Diubiquitin,Catalog Number:UD2801,Lyophilized,Purity95% Dha-K63-Diubiquitin. At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Dha-K6-Diubiquitin,Catalog Number:UD2201,Lyophilized,Purity95% At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Dha-K27-Diubiquitin,Catalog Number:UD2401,Lyophilized,Purity95% Dha-K27-Diubiquitin. At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Dha-K33-Diubiquitin,Catalog Number:UD2601,Lyophilized,Purity95% Dha-K33-Diubiquitin. At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Ubiquitin (Ub) is ubiquitous. This small, 76-residue protein is used to mark cellular proteins for degradation by the ubiquitin proteasome system (UPS). Two key enzyme families, Ub ligases and deubiquitylation enzymes (DUBs), are responsible for putting on and taking off these Ub units and controlling the overall protein population of the cell. As you might imagine, this dynamic process is important, and dysregulation can lead to an array of bad things. Thus, understanding

Types of histone modification Chromatin architecture, nucleosomal positioning, and ultimately access to DNA for gene transcription, is largely controlled by histone proteins. Each nucleosome is made of two identical subunits, each of which contains four histones: H2A, H2B, H3, and H4. Meanwhile, the H1 protein acts as the linker histone to stabilize internucleosomal DNA and does not form part of the nucleosome itself. Histone proteins undergo post-translational modification