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thrombin receptor Antagonist,Catalog Number: KS051005,CAS NO.:207553-92-2
The peptide, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. This peptide has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor. MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
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thrombin receptor Antagonist,Catalog Number: KS051005,CAS NO.:207553-92-2
The peptide, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. This peptide has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor. MSRPACPNDKYE has served as model peptide in protein modification and MS studies.