hematology peptides thrombin receptor online manufacturer Manufacturer

thrombin receptor Antagonist,Catalog Number: KS051005,CAS NO.:207553-92-2 The peptide, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. This peptide has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported

PAR-1 Agonist peptide,Catalog Number: KS051004,Molecular Weight:762.9 Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This protease-activated receptor-1 (PAR-1) selective peptide induces cyclooxygenase-2 (COX-2) protein and mRNA expression in human endothelial cells. Studies show that intratracheal instillation of the PAR1-specific peptide increases lung edema during high