ubiquitin probes polyubiquitination online manufacturer Manufacturer

Ub-Br2,Catalog Number: U1050,Lyophilized,Purity95% Ubiquitin-Br2 is C-terminally Bromoethylated Ub. Ub-Br2 can react with the active Cys through nucleophilic substitution. This probes exhibited distinct DUB profiling, enabling the identification of DUBs by affinity-tag based mass proteomics (AP-MS).

K11-Diubiquitin,Catalog Number: U2301,Lyophilized,Purity95% This K11 linked di-ubiquitin was obtained by chemical synthesis. K11 linked polyubiquitination increase when the metazoan anaphase-promoting complex APC/C is active during mitosis, and APC/C has been shown to assemble K11-linked ubiquitin chains to drive proteasomal degradation and exit from mitosis. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East

Dha-K27-Diubiquitin,Catalog Number:UD2401,Lyophilized,Purity95% Dha-K27-Diubiquitin. At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

K63-Diubiquitin,Catalog Number: U2801,Lyophilized,Purity95% This K63 linked di-ubiquitin was obtained by chemical synthesis. K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development. The array of cellular processes initiated and regulated by ubiquitin has been partially explained by the structural

K29-Diubiquitin,Catalog Number: U2501,Lyophilized,Purity95% This K29 linked di-ubiquitin was obtained by chemical synthesis. K29 linked polyubiquitination has been shown to be an inhibitor of Wnt signaling, which plays an important role in embryogenesis, and its deregulation has been shown to play a role in tumorigenesis.