ub br2 ubiquitin probes online manufacturer Manufacturer

Ub-Br2,Catalog Number: U1050,Lyophilized,Purity95% Ubiquitin-Br2 is C-terminally Bromoethylated Ub. Ub-Br2 can react with the active Cys through nucleophilic substitution. This probes exhibited distinct DUB profiling, enabling the identification of DUBs by affinity-tag based mass proteomics (AP-MS).

Ubiquitin (Ub) is ubiquitous. This small, 76-residue protein is used to mark cellular proteins for degradation by the ubiquitin proteasome system (UPS). Two key enzyme families, Ub ligases and deubiquitylation enzymes (DUBs), are responsible for putting on and taking off these Ub units and controlling the overall protein population of the cell. As you might imagine, this dynamic process is important, and dysregulation can lead to an array of bad things. Thus, understanding