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K48-Diubiquitin,Catalog Number: U2701,Lyophilized,Purity95% This K48 linked di-ubiquitin was obtained by chemical synthesis. Proteins polyubiquinated at specific lysine residues display a tendency to be targeted for different processes. The attachment of K48-linked polyubiquitin chains to proteins is a universal signal for degradation by the proteasome.
K63-Diubiquitin,Catalog Number: U2801,Lyophilized,Purity95% This K63 linked di-ubiquitin was obtained by chemical synthesis. K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development. The array of cellular processes initiated and regulated by ubiquitin has been partially explained by the structural