human urocortin neuropeptide peptides online manufacturer Manufacturer

Urocortin (human),CAS#:176591-49-4,Molecular Weight:4696.31 The peptide exhibits a strong binding affinity towards the types 1, 2a, and 2b corticotropin-releasing factor (CRF) receptors. It is capable of stimulating the accumulation of cyclic adenosine monophosphate (cAMP) from cells that have been transfected with these receptors. Moreover, in vitro experiments have shown that this peptide can induce the release of adrenocorticotropic hormone (ACTH) from dispersed rat

Urocortin (rat),CAS#:171543-83-2,Molecular Weight:4707.33 Peptide that is more potent than CRF at binding and activating type-2 CRF receptors and shares ~95% sequence with human version. As a mammalian neuropeptide related to fish urotensin and corticotropin-releasing factor, it also serves as an inducer of c-Fos in regions enriched in type-2 CRF receptors.