human ubiquitinated proteins online manufacturer Manufacturer

Ubiquitin,Catalog Number: U1000,Lyophilized,Purity95% This product is expressed in E.coli, composed of 76 amino acids. Ubiquitin is a small protein that exists in all eukaryotic cells. It performs its myriad functions through conjugation to a large range of target proteins. A variety of different modifications can occur. The ubiquitin protein itself consists of 76 amino acids and has a molecular mass of about 8.6 kDa. Key features include its C-terminal tail and the 7 lysine

Ub-Prg,Catalog Number: U1040,Lyophilized,Purity95%,Molecular Weight:8588.79 Ubiquitin-Prg is C-terminally propargylated Ub. Ub-Prg (also called Ub-PA) can react with the active Cys of DUBs through 1,2-addition to produce a stable vinyl thioether product. To explain regulatory mechanisms, Ub-Prg was used to capture the catalytic conformation by which RPN13DEUBAD activates UCH-L5; and the catalytic conformation that truncated INO80DEUBAD lacks to inhibit UCH-L5.

Dha-K11-Diubiquitin,Catalog Number:UD2301,Lyophilized,Purity95% At the isopeptide-bonding site, the distal ubiquitin-76 glycine mutates into dehydroalanine, which is used to trap the deubiquitinating enzyme. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Ub-Rho110,Catalog Number: UU1030,Lyophilized,Purity95% Ubiquitin-Rho110 is prepared by the C-terminal derivatization of ubiquitin with rhodamine 110. Compared with Ub-AMC, Ub-Rho110 has excitation and emission wavelengths ranging from 490 to 550 nm, it can effectively reduce the false positive results caused by autofluorescence of compounds.

Types of histone modification Chromatin architecture, nucleosomal positioning, and ultimately access to DNA for gene transcription, is largely controlled by histone proteins. Each nucleosome is made of two identical subunits, each of which contains four histones: H2A, H2B, H3, and H4. Meanwhile, the H1 protein acts as the linker histone to stabilize internucleosomal DNA and does not form part of the nucleosome itself. Histone proteins undergo post-translational modification

H2A-K13Ub Catalog Number H1401 Store at -20C or -80C This product is chemically synthesized histone H2A protein (1-129, human) with mono-ubiquitination at K13. Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. RNF168-mediated ubiquitination of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining

H2A-K15Ub Catalog Number H1402 Store at -20C or -80C Chemically synthesized histone H2A protein (1-129,human) with mono-ubiquitination at K15. Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. RNF168-mediated ubiquitination of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome stability.