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ACTH (1-13) (human),Catalog Number: KS061032,CAS 22006-64-0 ACTH (1-13) is a hormone produced and secreted by the pituitary gland. This peptide fragment is often referred to as the "corticotropin-releasing factor," as it binds to and activates specific receptors in the hypothalamus and pituitary gland, leading to the release of cortisol from the adrenal glands. ACTH (1-13) has been shown to be involved in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis, which
Urocortin (human),CAS#:176591-49-4,Molecular Weight:4696.31 The peptide exhibits a strong binding affinity towards the types 1, 2a, and 2b corticotropin-releasing factor (CRF) receptors. It is capable of stimulating the accumulation of cyclic adenosine monophosphate (cAMP) from cells that have been transfected with these receptors. Moreover, in vitro experiments have shown that this peptide can induce the release of adrenocorticotropic hormone (ACTH) from dispersed rat