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Description: High Performance Liquid Chromatography is an analytical technique for separating compounds in a sample matrix. Separation is achieved by dissolving the sample in a suitable solvent and injecting it into a stream of solvent called the mobile phase. The mobile phase (and injected sample) is passed through a stationary phase (HPLC column). The compounds exit the column at different times based on the affinity the compounds have for the mobile phase and the

Description: Using peptide mapping, subtle changes to the primary structure of a protein or antibody can be identified that may affect the activity of the protein or the binding affinity. Peptide mapping by LC-MS/MS is one of the most powerful qualitative assays to confirm the primary sequence of proteins or antibodies. This service can be used to compare different lots of the same proteins, antibodies or biosimilars. Service of peptide mapping analysis by LC-MS/MS includes: