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Urocortin (human),CAS#:176591-49-4,Molecular Weight:4696.31 The peptide exhibits a strong binding affinity towards the types 1, 2a, and 2b corticotropin-releasing factor (CRF) receptors. It is capable of stimulating the accumulation of cyclic adenosine monophosphate (cAMP) from cells that have been transfected with these receptors. Moreover, in vitro experiments have shown that this peptide can induce the release of adrenocorticotropic hormone (ACTH) from dispersed rat
