Fluorogenic MMP-2 Substrate,Catalog Number: KS121001,CAS NO.:256394-92-0
Sensitive substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. When cleaved at the Gly-Leu bond it separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher and results in the increase of fluorescence intensity. The kcat/km value for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7 x 105 and 6.3 x 105 M-1s-1, respectively.
Fluorogenic MMP-2 Substrate,Catalog Number: KS121001,CAS NO.:256394-92-0
Sensitive substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. When cleaved at the Gly-Leu bond it separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher and results in the increase of fluorescence intensity. The kcat/km value for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7 x 105 and 6.3 x 105 M-1s-1, respectively.