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Gastrin-Releasing Peptide (human),Catalog Number: KS042009,CAS NO.: 93755-85-2 Uroguanylin is a natriuretic peptide, a hormone that regulates sodium excretion by the kidney when excess NaCl is consumed. Uroguanylin and guanylin are related peptides that activate common guanylate cyclase signaling molecules in the intestine and kidney.