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-Secretase Substrate I(MCA-DNP pair),Catalog Number: KS012005,Sequence:MCA-HQKLVFFAK(DNP)-NH2 (trifluoroacetate salt) MCA-HQKLVFFA-K(DNP)-NH2 is a fluorogenic substrate for -secretase. Upon cleavage by -secretase, 7-methoxycoumarin-4-acetyl (MCA) is released and its fluorescence can be used to quantify -secretase activity. MCA displays excitation and emission maxima at 328 and 420 nm, respectively.
