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Urotensin II (human),Catalog Number: KS091013,CAS NO.:251293-28-4 Urotensin II (human) is a potent endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo, effects which vary between species. Also has been shown to mediate bronchoconstriction.

ANP (1-28); Carperitide,Catalog Number: KS063038,CAS NO.: 89213-87-6 Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, inhibit renin secretion, and increase sodium excretion. Human ANP binds to ANP receptors on cultured vascular smooth muscle cells (VSMCs) with a Kd value of approximately 1-2 nM

Angiotensin I (human),Catalog Number: KS092004,CAS NO.: 70937-97-2 Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II.

Adrenomedullin (1-52) (human),Catalog Number: KS091005,CAS NO.: 148498-78-6 Adrenomedullin (AM or ADM) is a peptide comprising 52 amino acids that was first identified in pheochromocytoma, a tumor of the adrenal medulla. Its nomenclature reflects its origin. Emerging evidence suggests that Adrenomedullin exerts various biological actions, such as vasodilation, cell proliferation, modulation of hormone secretion, natriuresis, and antimicrobial activity.

Angiotensin II (human),Catalog Number: KS063002,CAS NO.: 4474-91-3 Angiotensin II is an endogenous potent vasoconstrictor peptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE) by binding to both the AT1 and the AT2 receptors.

Copeptin (human),Catalog Number: KS091007,CAS NO.: 78362-34-2 This peptide derived from the vasopressin-neurophysin 2-copeptin precursor, a prognostic marker in a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failure and myocardial infarction.

Calcitonin Gene Related Peptide (rat),Catalog Number: KS062025,CAS NO.: 96827-03-1 Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach,

Apelin (1-13) (human),Catalog Number: KS021011,CAS NO.: 217082-58-1 Apelin 1-13 is a vasoactive peptide and one of the most potent endogenous inotropic agents known. It is one of the active peptide fragments resulting from maturation of preproapelin. It is suggested that Apelin 1-13 could be a competitive agonist to the apelin receptor, which is a class A G-protein coupled receptor and is a putative target for treatment of cardiovascular and metabolic diseases. Apelin 1-13

ANP (1-28); Carperitide,Catalog Number: KS062018,CAS NO.: 89213-87-6 Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, inhibit renin secretion, and increase sodium excretion. Human ANP binds to ANP receptors on cultured vascular smooth muscle cells (VSMCs) with a Kd value of approximately 1-2 nM

Intermedin (human),Catalog Number: KS091008,CAS NO.: 1188922-20-4 Intermedins are a part of the calcitonin/gene-related peptide (CGRP) family. In vitro experimentation has demonstrated that the synthetic 47 amino acid intermedin peptides act via the calcitonin receptor-like receptor/receptor activity-modifying protein (CRLR/RAMP) complexes by increasing the levels of intracellular cAMP. Unlike calcitonin gene-related peptide (CGRP) and adrenomedullin (ADM), intermedin does