dendrotoxin blocker online manufacturer Manufacturer

Dendrotoxin-I,CAS#:107950-33-4,Catalog Number:K1030-V,Store at -20C or -80C KV1.1, KV1.2 K+ channels, Dendrotoxin-I is a highly selective blocker of voltage-gated K+ channels (KV1.1 and KV1.2), as well as heteromultimeric channels containing these, with other KV1 isoforms1. The inhibition effect is higher in Xenopus oocytes compared to mammalian cells. Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australia,Asia,Middle East,Africa

Calcicludine (CaC) is a protein toxin from the venom of the green mamba that inhibits high-voltage-activated calcium channels, especially L-type calcium channels. Chemistry Calcicludine is a 60-amino acid polypeptide with six cysteines forming three disulfide bridges. Calcicludine structurally resembles dendrotoxin, but works differently, since even at high concentrations, calcicludine has no effect on dendrotoxin-sensitive potassium channels in chicken and rat neurons.